Nutanix and NVIDIA Enable Full-Stack Enterprise AI for Inferencing and Agentic Workflows

The Nutanix Cloud Platform (NCP) solution is now under development to support NVIDIA AI Data Platform. Announced at NVIDIA GTC 2025, NVIDIA AI Data Platform is a full-stack reference architecture to enable always-on, state-of-the-art indexing and retrieval performance for agentic AI. As enterprise AI becomes a critical business strategy for enterprises, certain challenges remain, such as time-to-value, AI talent acquisition, and realized productivity gains.

Nutanix is quickly becoming a solution for enterprise AI in production environments with a direct focus on resilience, security, and day 2 operations, helping accelerate AI strategies.

The Nutanix Cloud Platform (NCP) provides your choice of AI infrastructure and models enabling speed, efficiency, and security for all your private data, no matter where it resides. With the Nutanix GPT-in-a-Box™ solution, an AI hybrid cloud operating model becomes a reality. Customers focused on generative enterprise AI (GenAI) no longer have to choose between platforms for inferencing, tuning, or training, ensuring simplicity, cost, and control for their AI initiatives.

Let’s break down how the Nutanix Cloud Platform provides key capabilities across the NVIDIA AI Products and solutions, including NVIDIA AI Data Platform.

Nutanix is a Full-Stack Platform Built for Enterprise AI

NCP incorporates key AI platform components built to seamlessly deliver simplicity, control, and cost for enterprise AI inference and agents, including:

• Nutanix Enterprise AI (NAI), an AI Inferencing platform, delivering model choice and agentic capabilities integrated with NVIDIA NIM and NeMo microservices.
• Nutanix Database Service (NDB) for a managed and secure vector database deployment using PostgreSQL.
• Nutanix Kubernetes Platform (NKP) for enterprise Kubernetes management anywhere including on-premises private and public clouds
• Nutanix Unified Storage (NUS) and Nutanix Data Lens, for high-performing, cross cloud data control and availability, creating a consistent data experience for enterprise AI like secure data pipelines.
• Nutanix Cloud Infrastructure (NCI) with HCI for NVIDIA Accelerated Computing infrastructure like GPUs, network offload capabilities to support RDMA (Remote Direct Memory Access) and CX cards.

Data: The Key to Agentic AI

GenAI has exploded into the enterprise, promising productivity, unique insights, and personalized customer experiences. The initial steps to realize these promises involve planning, building, and deploying GenAI with LLMs, resulting in AI-driven apps like chatbots and code generation tools. However, most enterprises have massive amounts of data that have been previously difficult to include for various reasons:

• Multiple data silos across ecosystems
• Lack of a data pipeline to ingest, understand, and integrate key findings
• No clear path to integrating data for AI without specialized expertise, which is at a premium
• The need for a performant and secure data infrastructure to build and deploy agents

But now, there’s an answer to create the data architecture needed: NVIDIA AI Data Platform.

Announced at NVIDIA GTC 2025, this design provides a clear path to integrate your data for enterprise AI that simply performs. Built on NVIDIA Accelerated Computing using NVIDIA-Certified-Systems, this state-of-the-art reference design enables indexing and retrieval for the most demanding GenAI apps and agents.

Key components include:

• NVIDIA AI Enterprise that includes NIM, NeMo, and AI Blueprints for inferring and data processing of AI workflows
• Compute and Data nodes with ultra-fast storage capabilities
• NVIDIA Accelerated Computing components like GPUs

AI agents create a critical need for a solid data pipeline that can be fed into their workflows. The connection to, or hand off of these agents is particularly important for RAG - retrieval augmented generation, or providing your private data to an LLM (large language model) for added context to create content, enable chatbots, and drive customer experience.

So, how would you start building this architecture for the next frontier of AI from NVIDIA? The answer - the Nutanix Cloud Platform.

NCP for full stack enterprise AI helps deliver on every aspect of NVIDIA AI Data Platform for building and deploying production-grade AI experiences that are resilient, secure, and operational. Use cases and solutions surrounding delivering critical enterprise needs like inference and reasoning for agentic workflows like RAG are turnkey using Nutanix.

Kickstart Enterprise AI with Nutanix and NVIDIA

Nutanix and NVIDIA make enterprise AI simple, secure, and controlled no matter your AI focus. Key benefits include:

1. Simplified AI Model Deployment: Easily deploy, manage, and maintain generative AI models across various environments.
2. Accelerated Time-to-Value: Leverage our platforms to accelerate your organization's time-to-value for enterprise AI.
3. Operational Readiness: Enjoy operational readiness out-of-the-box with our unified platforms, ensuring minimal business disruption.
4. Industry-Leading Performance: Experience industry-leading performance and low latency with our cutting-edge technology.
5. Unified Platform: Benefit from a unified platform that simplifies the deployment, operation, and management of large-scale AI models.

Nutanix and NVIDIA help enable AI inferencing and agents wherever you run your AI workloads. As data becomes increasingly crucial—from data pipeline creation to simple model delivery—a full stack, production-ready solution is essential for success.  Nutanix makes it simple to make your AI strategy work with a resilient, secure, and operational solution today.

So, what’s your next move?

• Creating an AI data pipeline for tuning or training? Check out the latest blog from Nutanix Unified Storage on their latest NVIDIA announcements
• Want more? Go to nutanix.com/testdrive and get hands-on with Nutanix Enterprise AI at your own pace

About Nutanix

Nutanix is a global leader in cloud software, offering organizations a single platform for running apps and data across clouds. With Nutanix, organizations can reduce complexity and simplify operations, freeing them to focus on their business outcomes. Building on its legacy as the pioneer of HCI, Nutanix is trusted by companies worldwide to power hybrid multicloud environments consistently, simply, and cost-effectively. Learn more at www.nutanix.com or follow us on social media @nutanix.

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